Selenium and cancer prevention
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چکیده
منابع مشابه
Selenium and cancer prevention.
protection selenium provides against certain cancers that I have been taking daily selenium yeast supple ments (100-400 jxg)for 4 years, I am perplexed by the selection of cancers to be studied in related doubleblind clinical trials, namely those of the liver, skin and esophagus. In 1986, I published details of in excess of 13,000 correlations between the distributions of 219 environ mental var...
متن کاملSelenium and cancer prevention
The essential trace mineral, selenium, has been the focus of an increasing number of research studies since the 1996 report that it decreased the risk of some common cancers. Prospective studies have generally shown some benefit of higher selenium status on the risk of prostate, lung, colorectal, and bladder cancers but trials have had mixed findings, likely highlighting the fact that supplemen...
متن کاملSelenium and Prostate Cancer Prevention: Insights from the Selenium and Vitamin E Cancer Prevention Trial (SELECT)
The Selenium and Vitamin E Cancer Prevention Trial (SELECT) was conducted to assess the efficacy of selenium and vitamin E alone, and in combination, on the incidence of prostate cancer. This randomized, double-blind, placebo-controlled, 2 × 2 factorial design clinical trial found that neither selenium nor vitamin E reduced the incidence of prostate cancer after seven years and that vitamin E w...
متن کاملSelenium and vitamin E cancer prevention trial.
Preclinical, epidemiological, and phase III data from randomized, placebo-controlled clinical trials suggest that both selenium and vitamin E have potential efficacy in prostate cancer prevention. In vitro evidence suggests that selenium and vitamin E work synergistically to cause cell-cycle arrest, induce caspase-mediated apoptosis, and act as antiandrogens in arresting clonal expansion of nas...
متن کاملSelenium: from cancer prevention to DNA damage.
Selenium (Se) is a dietary essential trace element with important biological roles. Accumulating evidence indicates that Se compounds possess anticancer properties. Se is specifically incorporated into proteins in the form of selenocysteine and non-specifically incorporated as selenomethionine in place of methionine. The effects of Se compounds on cells are strictly compositional and concentrat...
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ژورنال
عنوان ژورنال: Hereditary Cancer in Clinical Practice
سال: 2012
ISSN: 1897-4287
DOI: 10.1186/1897-4287-10-s4-a1